Ji Hong is a doctor who decided to become a high school teacher. He meets Hye Jung, a reckless student who happens to be his favorite neighbor's granddaughter and turns out to be his student. Their deep relationship led them to be accused of being in a romantic student-teacher relationship. 13 years later, they suddenly bump into each other under neurosurgery in the same hospital. Hye Jung is determined to avenge her grandmother's death due to medical malpractice, as Ji Hong is out to protect his highschool sweetheart. In between, they face numerous challenges in the operating room, within their relationship, and the political disputes within the hospital and its investors.

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